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Activation of a maize alpha-tubulin promoter and tubulin location in mycorrhizal transgenic tobacco roots

poster/talk
5.Gene Expression
BONFANTE, PAOLA1, A. GENRE1, R. BERGERO1, P. PUIGDOMENECH2
1Dipartimento di Biologia vegetale dell'Università, CSMT-CNR, Viale Mattioli 25, 10125 Torino, Italy
2Departament de Genetica Molecular. CID-CSIC. Jordi Girona, 18. 08034 Barcelona, Spain

ICOM1 Abstract
Transformed tobacco plants are good hosts for AM fungi and were used to test the hypothesis that changes in the expression of cytoskeleton genes are involved in the substantial morphological modifications described in root cells upon fungal colonization. Tobacco plants containing constructs where the promoters of either a maize a1 or an a3 tubulin gene were fused with the GUS reporter gene showed an intense GUS activity in the meristematic region. When colonized by Gigaspora margarita, only plants with the tuba3 construct showed gene activation in the differentiated root regions. We have detected i) GUS activity in the cortical root cells which contain arbuscules, and ii) accumulation of a3 tubulin transcripts in maize root cells where arbuscules are formed. Immunofluorescence experiments revealed an altered pattern of expression of alpha and beta tubulins in the infected cells. Microtubules organization in the apical root meristeme reveals the different mitotic phases, while microtubular bundles in the parenchymatic cortical cells showed reduction both in thickness and in number. The penetration of the symbiotic fungus into these cortical cells caused a change in organization of microtubules. They run along the intracellular hyphae and the arbuscular trunk, and branch around the small arbuscular hyphae as short bundles. In conclusion, on the basis of GUS technology and in situ hybridization, we offer evidence that tuba3 gene changes its expression during establishment of symbiosis with AM fungi in both maize and transgenic tobacco. In addition, immunofluorescence clearly reveals that microtubules represent another cellular compartment that changes its organization upon fungal colonization.